Vitiligo




Def:Absence of melanocytes
Lesion are nonpigmented

Cause
MC Genetic 20-30%
Antimelanocyte autoantibodies
Free radical accumulation

        Age
        MC 10 -30 yrs

Disease association
Trick      man become Mota(diabetic) by adding anemia

Man                 MEN
Motto(Mota)  hashimoto thyroiditis     
Diabetic          diabetes mellitus
Add the.         Addison dis.
Anemia          pernicious anemia

          CF:
          Hallmark depigmented macule

Location
Any part of body

       Pattern
       MC vitilgo vulgaris

Treatment
PUVA  mainstay     trick { vitiligo ka puvva)

        Drug
        Topical steroid
        Tacrolimus
at
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