Vasalgel is a long-acting, nonhormonal contraceptive with a significant advantage over vasectomy: it is likely to be more reversible. The procedure is similar to a no-scalpel vasectomy, except a gel is injected into the vas deferens (the tube the sperm swim through), rather than cutting the vas (as is done in vasectomy). If a man wishes to restore flow of sperm, whether after months or years, the polymer is flushed out of the vas with another injection.
Vasalgel was inspired by the work on a polymer contraceptive called RISUG®, which is in advanced clinical trials in India; some of the men have been using RISUG® for more than 15 years. But right now, only local men near the study sites in India are eligible for the trials, and formal reversibility studies have only been done in animals, not men.
In early 2010, Parsemus Foundation began developing a polymer contraceptive for the rest of the world outside India. The new polymer contraceptive is called Vasalgel™, and 12 months of rabbit studies have shown no sperm from the second semen sample onwards! Sperm flow quickly returned in rabbits that had the polymer flushed out. The goal is to have it on the market as an alternative to vasectomy as soon as possible, with the first clinical trial has started in 2016.
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